Short-term result of collagen crosslinking in pellucid marginal degeneration. Mamoosa B, Razmjoo H, Peyman A, Ashtari A, Ghafouri I, Moghaddam AG. Descemet detachment after femtosecond-laser-assisted placement of intrastromal ring segments in pellucid marginal degeneration. Intrastromal ring segment insertion using a femtosecondlaser to correct pellucid marginal corneal degeneration. Sclerocorneal Intrastromal Lamellar Keratoplasty for Pellucid Marginal Degeneration. Guindolet D, Petrovic A, Doan S, Cochereau I, Gabison EE.
Scleral contact lenses in the management of pellucid marginal degeneration. Rathi VM, Dumpati S, Mandathara PS, Taneja MM, Sangwan VS. Clinical outcomes of scleral Misa lenses for visual rehabilitation in patients with pellucid marginal degeneration. Characteristics of ocular higher-order aberrations in patients with pellucid marginal corneal degeneration. Oie Y, Maeda N, Kosaki R, Suzaki A, Hirohara Y, Mihashi T, et al. Characteristics of corneal topographic and pachymetric patterns in patients with pellucid marginal corneal degeneration. 17 (2):246-8.įuchihata M, Maeda N, Toda R, Koh S, Fujikado T, Nishida K. Unilateral pellucid marginal degeneration. 6 (2):191-9.īasak SK, Hazra TK, Bhattacharya D, Sinha TK. Corneal Hydrops in Pellucid Marginal Degeneration: A Case Series. Refractive and Corneal Aberrometric Changes After Crescentic Lamellar Wedge Resection in Pellucid Marginal Degeneration. National survey of pellucid marginal corneal degeneration in Japan. Shimazaki J, Maeda N, Hieda O, Ohashi Y, Murakami A, Nishida K, et al. Management of pellucid marginal corneal degeneration. Tzelikis PF, Cohen EJ, Rapuano CJ, Hammersmith KM, Laibson PR. Management of pellucid marginal corneal degeneration with rigid gas permeable contact lenses. Sridhar MS, Mahesh S, Bansal AK, Nutheti R, Rao GN. Keratoconus and related noninflammatory corneal thinning disorders. “Corneal topography is a powerful tool for the early diagnosis of PMD,” he said.Krachmer JH. PMD is most commonly misdiagnosed as inferior keratoconus. “Mild cases of PMD are difficult to detect with slit lamp examination alone,” Shimazaki said. Unlike keratoconus, stromal striae and iron ring are not seen in PMD cases, and physicians should be aware that acute hydrops may occur in patients with the disease. Glasses may also be used, but refractive surgery should be avoided. Crescentic lamellar keratoplasty and crescentic wedge excision can also be considered, he said.Ĭontact lenses, including gas-permeable hard, hybrid or scleral lenses, are the most common form of medical management for PMD, Shimazaki said. Collagen cross-linking may be useful for halting disease progression, as well as the use of an intracorneal ring segment or corneal transplantation. Proper management of pellucid marginal corneal degeneration (PMD) is important, Shimazaki said, and visual disturbances may develop later and continue to progress. “There is no detailed epidemiological data, and unilateral cases constitute 25% of all patients.” Source: Adobe stock.
“The pathogenesis of PMD remains unclear, and no genetic cause has been found,” Jun Shimazaki, MD, PhD, said at Cornea Subspecialty Day at the American Academy of Ophthalmology meeting. If you continue to have this issue please contact to HealioĬHICAGO - Pellucid marginal corneal degeneration is a rare disease, but early diagnosis is necessary to ensure patients’ quality of life, according to a speaker.
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